基于“癌毒传舍”理论防治肺癌转移

来源:用户上传      作者:钟佳 刘华 王理槐

　　 〔摘要〕 基于“癌毒传舍”理论防治肺癌转移，从癌毒特点、“传之路径”、易“舍”之脏三方面出发，将扶正祛邪、化痰祛瘀法贯穿治疗的始终。腺癌、鳞癌、小细胞肺癌癌毒分别以痰热毒的偏盛为特点，故治疗分别侧重化痰、清热、攻毒。癌毒“传之路径”乃气血运行、津液输布的通道，治疗着重化痰祛瘀。肺癌癌毒最易“舍”于肝、脑、骨、淋巴结，肝转移癌防治注重疏肝健脾，活血散结。脑转移癌防治注重化痰息风，活血通窍。骨转移癌防治注重补肾填精，化瘀生新。淋巴结转移癌防治注重化痰祛瘀，软坚散结。
　　 〔关键词〕 癌毒传舍;肺癌;肝转移癌;脑转移癌;骨转移癌;淋巴结转移癌;转移
　　 〔中图分类号〕R273 〔文献标志码〕A 〔文章编号〕doi：10.3969/j.issn.1674-070X.2021.12.023
　　Discussion on the Prevention and Treatment of the Metastasis of Lung Cancer Based on
　　“Cancer Toxic’s Dissemination and Setting Down” Theory
　　ZHONG Jia1， LIU Hua2*， WANG Lihuai2
　　（1. Hunan University of Chinese Medicine， Changsha， Hunan 410208， China; 2. The First Affiliated Hospital of Hunan University of Chinese Medicine， Changsha， Hunan 410007， China）
　　〔Abstract〕 Based on the theory of “cancer toxic’s dissemination and setting down” to prevent and treat lung cancer metastasis， the method of reinforcing the healthy Qi and eliminating the pathogenic factors， resolving phlegm and eliminating stasis are important through the whole process， from the characteristics of cancer toxin， “transmission path”， viscera easy to “give up” three aspects. The “cancer toxins” of adenocarcinoma， squamous cell carcinoma， and small cell lung cancer are characterized by phlegm “heat”， and treatment focuses on removing phlegm， clearing away heat， and detoxify. The path of “cancer toxin’s dissemination” is the channel for the circulation of Qi and blood and the transfusion of body fluid， resolving phlegm and removing blood stasis should be emphasized. The “cancer toxin” of lung cancer is most easily metastasize to the liver， brain， bones and lymph gland. The prevention and treatment of liver metastatic cancer focuses on soothing the liver and fortifying the spleen， promoting blood circulation and dispersing nodules. The prevention and treatment of brain metastasis cancer focuses on resolving phlegm to relieve wind， activating blood and opening the orifices. The prevention and treatment of bone metastatic cancer focuses on tonifying the kidney and filling essence， dispelling stasis to promote regeneration. The prevention and treatment of lymph node metastasis focuses on resolving phlegm and removing blood stasis， softening hardness and dissipating binds respectively.
　　〔Keywords〕 cancer toxic’s dissemination and setting down; lung cancer; liver metastases; brain metastases; bone metastases; lymph node metastasis; transfer
　　肺癌是中发病率与死亡率最高的恶性肿瘤，在全球范围内，2020年肺癌在男性总体癌症中的发病率为14.3%，位居第一，在女性总体癌症中的发病率为8.4%，位居第三，肺癌是导致癌症死亡的首要原因，在全部癌症死因中占18.0%[1]。目前，部分国家与地区的肺癌发病率与死亡率已较之前下降，但肺癌患者的预后仍不容乐观[2-3]。近年来，靶向、免疫等治疗手段日益更新，新药物不断涌现，延长了肺癌患者的生存期，但肺癌的复发转移仍是临床治疗难点。据统计，约90%肺癌患者死于复发转移[4]。初始治疗后出现复发转移，放疗、化疗、靶向治疗、免疫治疗的相关毒副反应，往往使患者对后续治疗失去信心，依从性下降。中医药干预有助于遏制肺癌转移，缓解西医治疗相关不良反应，提高患者治疗的积极性，亦是防治肺癌转移的重要手段。
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