左西替利嗪、孟鲁司特联合卡介菌素对慢性荨麻疹的治疗效果分析
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作者:刘国芳 张志杰
摘 要：目的 研究左西替利嗪、孟司特联合卡介菌素治疗慢性荨麻疹的效果。方法 选取山东第一医科大学附属肥城医院2019年2月～2020年11月收治的慢性荨麻疹患者78例，按随机数表法分为对照组和观察组，每组39例。对照组采用卡介菌素联合孟鲁司特治疗，观察组采用左西替利嗪、孟鲁司特联合卡介菌素治疗。比较两组患者生活质量评分、治疗效果、临床症状消退时间。结果 治疗后，观察组患者临床症状消退时间显著短于对照组，差异有统计学意义（P<0.05）。治疗后，观察组患者治疗效果显著高于对照组，差异有统计学意义（P<0.05）。治疗后，观察组患者生活质量评分显著高于对照组，差异有统计学意义（P<0.05）。结论 左西替利嗪、孟鲁司特联合卡介菌素治疗慢性荨麻疹，能够缩短患者临床症状消退时间，提升患者治疗效果，同时提升患者生活质量，能够给临床治疗慢性荨麻疹方面提供更多的参照，并可在临床应用。
关键词：左西替利嗪;治疗;孟鲁司特;卡介菌素;慢性荨麻疹
中图分类号：R758.24 文献标识码：A 文章编号：1009-8011（2022）-8-000-04
Analysis of the Therapeutic Effect of Levocetirizine， Montelukast combined with BCG on Chronic Urticaria
LIU Guo-fang1 ZHANG Zhi-jie2
（1.Department of Dermatology and Venereology， Feicheng Hospital Affiliated to Shandong First Medical University，Tai’an Shandong 271600， China; 2.The Second Department of Surgery， Feicheng Hospital of Traditional Chinese Medicine， Tai’an Shandong 271600， China）
Abstract： Objective To study the the therapeutic effect of levocetirizine， montelukast combined with BCG Bacillus Calmette-Guerin on chronic urticaria patients. Methods A total of 78 patients with chronic urticaria admitted to Feicheng Hospital Affiliated to Shandong First Medical University from February 2019 to November 2020 were selected. They were included and randomly divided into the observation group and the control group. Among them， 39 patients in the observation group received the therapy proctocol of levocetirizine， montelukast combined with BCG， while 39 patients in the control group received Bacillus Calmette-Guerin combined with montelukast. Quality of life score， treatment efficacy and clinical symptom subsidence time were administated between two groups. Results After treatment， the clinical symptom subsidence time in the observation group was significantly shorter than that in the control group （P<0.05）. After treatment， the total efficiency of the observation group was significantly higher than that of the control group （P<0.05）. After treatment， the quality of life score of the observation group was significantly higher than that of the control group （P<0.05）. Conclusion The therapy protocol of levocetirizine， montelukast combined with BCG in chronic urticaria could significatly improve the clinical symptom subsidence time， improve the therapeutic effect and increase the quality of life score.
Keywords： levocetirizine; montelukast; Bacillus Calmette-Guerin; chronic urticaria
nlc202204271722
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