畲药食凉茶联合针灸治疗非酒精性脂肪性肝病的临床疗效及其安全性评估

来源:用户上传      作者:袁淑芬　　叶�Z　　王丽琴　　刘鸿

　　[摘要] 目的 探讨非酒精性脂肪性肝病患者采用针灸联合畲药食凉茶治疗的临床价值。方法 随机将2020年1月至2021年1月期间浙江省丽水市中医院收治的非酒精性脂肪性肝病患者104例分为两组，对照组采用常规治疗，而观察组则运用畲药食凉茶与针灸联合治疗，比较两组各项观察指标。结果 治疗前，两组BMI水平比^差异无统计学意义（P>0.05）;治疗后，观察组的BMI低于对照组（P<0.05）;观察组的HDL-C高于对照组，且LDL-C、TG及TC高于对照组（P<0.05）;观察组的治疗有效率高于对照组（P<0.05）;治疗前，两组肝功能指标比较差异无统计学意义（P>0.05）;与对照组比较，观察组的AST和ALT水平较低，差异有统计学意义（P<0.05）;两组治疗前的中医证候积分比较，差异无统计学意义（P>0.05）;观察组治疗后的中医证候积分低于对照组（P<0.05）;同时，两组的肝纤维化指标比较，差异有统计学意义（P<0.05）;但是两组的不良反应发生率比较，差异无统计学意义（P>0.05）。结论 临床上运用畲药食凉茶和针灸对非酒精性脂肪性肝病患者进行治疗，不仅能够使治疗效果提高，改善患者肝功能，还可以减少不良反应，安全性较高，值得推广。
　　[关键词] 非酒精性脂肪性肝病;针灸;畲药食凉茶;肝功能
　　[中图分类号] R575.55 [文献标识码] B [文章编号] 1673-9701（2022）09-0137-03
　　Clinical efficacy and safety evaluation of She Medicine Shi Liang Cha combined with acupuncture in the treatment of nonalcoholic fatty liver disease
　　YUAN Shufen1 YE Jing2 WANG Liqin1 LIU Hong1
　　1.Department of Acupuncture and Moxibustion， Lishui Chinese Medicine Hospital， Lishui 323000， China; 2.Department of Infectious Diseases， Lishui Central Hospital， Lishui 323000， China
　　[Abstract] Objective To investigate the clinical value of acupuncture and moxibustion combined with She Medicine Shi Liang Cha in treating patients with nonalcoholic fatty liver disease. Methods 104 patients with nonalcoholic fatty liver disease admitted to our hospital from January 2020 to January 2021 were randomly divided into two groups. The control group was treated with routine treatment， while the observation group was treated with She Medicine Shi Liang Cha combined with acupuncture. The indicators of the two groups were compared. Results Before treatment， there was no significant difference in BMI level between the two groups （P>0.05）. After treatment， the BMI level in the observation group was lower than that in the control group （P<0.05）. Compared with the control group， the levels of TC， TG， and LDL-C in the observation group were decreased， and the level of HDL-C was increased， with a significant difference between groups （P<0.05）. The treatment efficiency in the observation group was higher than that in the control group （P<0.05）. Before treatment， there was no significant difference in the liver function indicators between the two groups （P>0.05）. After treatment， the ALT and AST levels in the observation group were lower than those in the control group （P<0.05）. There was no difference in Chinese medicine syndrome scores between the two groups before treatment （P>0.05）. After treatment， compared with the control group， the Chinese medicine syndrome scores of the observation group decreased， and there was a difference between the groups （P<0.05）. There were significant differences in liver fibrosis indexes between the two groups （P<0.05）. However， there was no significant difference in the incidence rate of adverse reactions between the two groups （P>0.05）. Conclusion The clinical use of She medicine Shi Liang Cha and acupuncture in the treatment of patients with nonalcoholic fatty liver disease can improve the therapeutic effect and improve the liver function of patients and reduce adverse reactions， with high safety. It is worthy of being widely popularized.

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