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芪骨胶囊在老年骨质疏松女性股骨颈骨折术后疗效分析

来源:用户上传      作者:彭鹏 臧剑 许冠伟 魏秋实

  [摘要] 目的 u价芪骨胶囊联合人工股骨头置换术治疗老年骨质疏松女性患者股骨颈骨折的疗效。 方法 选择2019年3月至2021年3月珠海市中西医结合医院收治的106例70~85岁患骨质疏松因外伤致股骨颈骨折女性患者,随机数字法分为对照组与研究组,每组各53例。对照组进行人工股骨头置换术治疗,研究组在对照组基础上进行芪骨胶囊口服治疗。比较两组的髋关节功能评分量表(harris svore,Harris)、运动功能评分(Fug1-Meyer motor assessment,Fugl-Meyer)、Berg平衡量表(Berg balance scale,BBS)及疼痛评分(visual analogue scale/score,VAS)、治疗有效率、大转子、股骨颈骨密度、椎体前缘高度和椎体中间高度等。 结果 治疗后,对照组、研究组的Harris评分分别为(69.1±4.1)分、(76.5±4.5)分,Fugl-Meyer评分分别为(16.6±2.2)分、(24.5±2.2)分,Berg评分分别为(2.1±0.1)分、(1.1±0.2)分,VAS评分分别为(4.2±0.6)分、(2.1±0.4)分,两组的Harris、Fugl-Meyer评分均明显升高,Berg、VAS评分均明显降低,但与对照组比较,研究组变化更明显(P<0.05);与对照组比较,研究组的治疗有效率更高(P<0.05);对照组、研究组的大转子密度分别为(555.8±21.7)mg/cm2、(564.3±22.5)mg/cm2,股骨颈密度分别为(615.8±13.2)mg/cm2、(719.3±13.6)mg/cm2,治疗后,两组的大转子、股骨颈骨密度均明显升高,但相较对照组,研究组升高更明显(P<0.05);对照组、研究组的Cobb角分别为(13.5±4.7)°、(11.8±3.9)°,椎体前缘高度分别为(20.8±4.8)mm、(22.1±4.9)mm,椎体中间高度分别为(21.8±4.2)mm、(23.5±4.6)mm,研究组的椎体前缘高度和椎体中间高度高于对照组(P<0.05),Cobb角低于对照组(P<0.05)。 结论 芪骨胶囊联合人工股骨头置换术治疗老年骨质疏松性股骨颈骨折,可加速促进髋部骨密度增加,减少并发症发生,降低疼痛程度,促进髋关节功能恢复。
  [关键词] 芪骨胶囊;人工股骨头置换术;老年;骨质疏松;股骨颈骨折
  [中图分类号] R683.42 [文献标识码] B [文章编号] 1673-9701(2022)13-0070-05
  [Abstract] Objective To evaluate the efficacy of Qigu Capsule combined with artificial femoral head replacement in the treatment of femoral neck fracture in elderly female patients with osteoporosis. Methods A total of 106 female patients aged 70-85 years old with osteoporosis and trauma-induced femoral neck fracture admitted to Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine from March 2019 to March 2021 were selected as study subjects. They were divided into the control group and the study group according to the random number method,with 53 cases in each group.The control group was treated with artificial femoral head replacement,while the study group was treated with oral Qigu capsule on the basis of the treatment in the control group.The hip function rating scale(harris score, harris), motor function score(fug1-meyer motor assessment, fugl-meyer),berg balance scale (BBS) and pain score (Visual analogue scale/score, VAS),effective rate of treatment, greater trochanter and femoral neck bone density, anterior height of vertebral body and mid-height of vertebral body were compared between the two groups. Results After treatment, Harris scores were (69.1±4.1)points and (76.5±4.5)points, Fugl-Meyer scores were (16.6±2.2)points and (24.5±2.2)points, Berg scores were (2.1±0.1)points and (1.1±0.2)points, and VAS scores were (4.2±0.6)points and (2.1±0.4)points in the control group and the study group,respectively.Harris and Fugl-Meyer scores in both groups were significantly higher, while Berg and VAS scores were significantly lower than those before treatment,and the change of scores before and after treatment was more significant in the study group than that in the control group(P<0.05).The effective rate of treatment in the study group was higher than that in the control group(P< 0.05). After treatment, the greater trochanter density was (555.8±21.7)mg/cm2 and (564.3±22.5)mg/cm2, and the femoral neck bone density was (615.8±13.2)mg/cm2 and (719.3±13.6)mg/cm2 in the control group and the study group,respectively.The greater trochanter and femoral neck bone density in both groups increased significantly compared with those before treatment,and the range of the increase in the study group was more significant than that in the control group(P<0.05). The Cobb angle was (13.5±4.7)° and (11.8±3.9)°, the anterior height of vertebral body was (20.8±4.8)mm and (22.1±4.9)mm,and the mid-height of vertebral body was (21.8±4.2)mm and (23.5±4.6)mm in the control group and the study group, respectively. The anterior height of vertebral body and the mid-height of vertebral body in the study group were higher than those in the control group(P<0.05),while the Cobb angle was smaller than that in the control group(P<0.05). Conclusion In the treatment of osteoporosis complicated with femoral neck fracture in the elderly, Qigu Capsule combined with artificial femoral head replacement can accelerate the increase of hip bone density, reduce the occurrence of complications, decrease the degree of pain and promote the recovery of hip function.

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