强脉冲光联合调Q激光治疗雀斑的有效性及安全性分析

来源:用户上传      作者:韩朋 张洁 王艳玲 马云鹏

　　[摘要]目的：探强脉冲光（IPL）联合调Q激光治疗雀斑的疗效及其安全性。方法：选取2018年1月-2020年10月在笔者医院整形外科就诊的雀斑患者110例。按随机数字法分为对照组和观察组，各55例。对照组采用IPL治疗，观察组采用IPL联合调Q激光治疗。比较两组临床疗效、雀斑严重程度与累及范围（PSI）评分、不良反应情况、满意度情况及生活质量评分。结果：观察组总有效率94.55%高于对照组81.82%（P<0.05）。治疗后，两组PSI评分均低于治疗前，且观察组低于对照组（P<0.05）。两组不良反应总发生率比较，差异无统计学意义（P>0.05）。观察组总满意度90.91%高于对照组74.55%（P<0.05）。治疗后，两组生活质量评分均高于治疗前，且观察组高于对照组（P<0.05）。结论：IPL联合调Q激光治疗雀斑具有良好的效果，可减轻皮损症状，提高患者满意度，改善生活质量，且不增加不良反应。
　　[关键词]雀斑;强脉冲光;调Q激光;疗效;安全性
　　[中图分类号]R758.4+3 [文献标志码]A [文章编号]1008-6455（2022）05-0006-04
　　Analysis of the Effectiveness and Safety of Intense Pulsed Light Combined with Q-switched Laser in the Treatment of Freckles
　　HAN Peng，ZHANG Jie，WANG Yanling，MA Yunpeng
　　（Department of Plastic Surgery，the Second Hospital of Hebei Medical University，Shijiazhuang 050000，Hebei，China）
　　Abstract： Objective To investigate the efficacy and safety of intense pulsed light （IPL） combined with Q-switched laser in the treatment of freckles. Methods Total of 110 patients with freckles who were treated in the plastic surgery department of our hospital from January 2018 to October 2020 were selected. According to the random number method， the patients were divided into the control group （n=55） and the observation group （n=55）. The control group was treated with IPL， and the observation group was treated with IPL combined with Q-switched laser. The clinical efficacy， pigmentation area and severity index （PSI） score， incidence of adverse reactions， satisfaction and quality of life scores were compared between the two groups. Results The total effective rate of the observation group （94.55%） was higher than that of the control group （81.82%）， and the difference was statistically significant （P<0.05）. After treatment， the PSI scores of the two groups were all lower than those before treatment， and the PSI scores of the observation group was lower than the control group， and the difference were all statistically significant （P<0.05）. There was no significant difference in the total incidence of adverse reactions between the two groups （P>0.05）. The total satisfaction of the observation group （90.91%） was higher than that of the control group （74.55%）， and the difference was statistically significant （P<0.05）. After treatment， the quality of life scores of the two groups were all higher than before treatment， and the quality of life scores of the observation group was higher than the control group， and the difference were all statistically significant （P<0.05）. Conclusion IPL combined with Q-switched laser has a good effect in the treatment of freckles， which can reduce the symptoms of skin lesions， improve patient satisfaction， improve the quality of life， and does not increase adverse reactions.

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