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  • 苏子降气汤联合康复呼吸训练对慢性阻塞性肺疾病稳定期患者肺功能的影响

苏子降气汤联合康复呼吸训练对慢性阻塞性肺疾病稳定期患者肺功能的影响

来源:用户上传      作者:王磊 顾检波 花艳

  摘 要 目的:探讨苏子降气汤联合康复呼吸训练对慢性阻塞性肺疾病(COPD)稳定期患者肺功能的影响。方法:将COPD稳定期患者随机分为对照组(n=69)和观察组(n=70),对照组采用噻托溴铵联合康复呼吸训练治疗,观察组在对照组的基础上给以苏子降气汤治疗,比较两组临床疗效和肺功能改善情况。结果:观察组总有效率、肺功能指标、血氧饱和度、动脉血氧分压以及6 min步行测试距离均高于对照组;呼吸功能、生活质量评分和二氧化碳分压均低于对照组(均P<0.05)。结论:苏子降气汤联合康复呼吸训练治疗COPD能有效改善患者肺功能和呼吸功能。
  关键词 COPD 苏子降气汤 康复呼吸训练 噻托溴铵 肺功能
  中图分类号:R289.5; R563 文献标志码:A 文章编号:1006-1533(2022)09-0027-04
  引用本文 王磊, 顾检波, 花艳. 苏子降气汤联合康复呼吸训练对慢性阻塞性肺疾病稳定期患者肺功能的影响[J].上海医药, 2022, 43(9): 27-30; 46.
  Effect of Suzi Jiangqi decoction combined with respiratory rehabilitation training on pulmonary function in patients with chronic obstructive pulmonary disease at the stable stage
  WANG Lei, GU Jianbo, HUA Yan
  (Department of Internal Medicine, Zhitang People’s Hospital of Changshu, Changshu 215531, China)
  ABSTRACT Objective: To explore the effect of Suzi Jiangqi decoction combined with respiratory rehabilitation training on pulmonary function in patients with chronic obstructive pulmonary disease (COPD) at the stable stage. Methods: The patients were randomly divided into a control group (n=69) and an observation group (n=70). The control group was treated with tiotropium bromide combined with respiratory rehabilitation training, while the observation group was additionally treated with Suzi Jiangqi decoction on the basis of the control group. The clinical efficacy and the improvement of pulmonary function were compared between the two groups. Results: The total effectiveness and the index of pulmonary function and the arterial oxygen saturation were higher and 6-minute walk distance was longer and the score of respiratory function and the quality of life and the partial pressure of carbon dioxide were lower in the observation group than the control group (all P<0.05). Conclusion: Suzi Jiangqi decoction combined with respiratory rehabilitation training can effectively improve patients’ pulmonary function and respiratory function.
  KEY WORDS COPD; Suzi Jiangqi decoction; respiratory rehabilitation training; tiotropium bromide; pulmonary function
  慢性阻塞性肺疾病(chronic obstructive pulmonary disease, COPD),称慢阻肺,是一种与气道和肺脏对有毒颗粒或气体的慢性炎性反应增强有关的疾病,具有较高的发病率和致死率[1]。资料表明,我国COPD患者目前已经超过1亿人,且患病人数逐年增加。COPD分为稳定期和急性发作期,对于稳定期的治疗,以改善临床症状,延缓肺功能和呼吸功能,防止急性加重,提高患者生活质量为主要原则[2]。噻托溴铵等支气管扩张剂、地塞米松等糖皮质激素、N-乙酰半胱氨酸、羧甲司坦等抗氧化剂以及盐酸氨溴索、盐酸溴己新等祛痰剂是目前COPD稳定期常用的治疗药物[3]。虽然这些药物在一定程度上可以改善患者的肺功能,但不能根治COPD,且部分患者长期用药容易形成耐药性,远期的疗效较差[4]。中医药在治疗COPD方面积累了丰富的经验,中医康复呼吸训练、中药汤剂内服、针灸理论等中医药手段均对COPD有一定的疗效[5-6]。很多中药方剂如三子养亲汤、苏子降气汤等也对COPD有一定的疗效[7]。在临床上,应用苏子降气汤联合康复呼吸训练治疗COPD稳定期患者疗效显著,可有效改善患者的肺功能,现将探究结果报道如下。

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