中西医联合治疗老年性骨质疏松胸腰椎压缩性骨折的临床疗效分析

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　　[摘要] 目的 研究分析老年性骨質疏松胸腰椎压缩性骨折患者实施补肾健康汤联合西药治疗的应用效果及临床疗效。 方法 方便选择60例该院收治的老年性骨质疏松胸腰椎压缩性骨折的患者，2017年10月—2018年10月作为该研究的时间范围，采用随机数字表法将其分为实验组与参照组，各30例。其中参照组：单纯的使用西药治疗，实验组：补肾健骨汤联合西药治疗，对比两组患者的临床治疗效果以及两组患者的治疗前后的骨密度变化情况、两组患者治疗前后的Frankel脊髓损伤分级以及两组合的并发症和不良反应发生情况。比较两组患者的疼痛感觉，疼痛感觉测定方法为疼痛模拟视觉评分。 结果 ①治疗前，实验组骨密度是（-3 310.48±102.11）mg/cm3，对照组骨密度是（-3 311.38±100.01）mg/cm3，两组老年性骨质疏松胸腰椎压缩性骨折患者的骨密度具有一致性（t=0.034，P>0.05），治疗后，实验组骨密度是（-1 000.48±100.02）mg/cm3，对照组骨密度是（-1 408.48±103.21）mg/cm3，两组患者的骨密度均有所提升，较治疗前骨密度差异有统计学意义（t=15.549，P<0.05）。实验组的患者的骨密度情况明显优于参照组，两组之间的组间差异有统计学意义（P<0.05）。②实验组老年性骨质疏松胸腰椎压缩性骨折患者临床治疗有效率（96.66%）与参照组（66.66%）相比较高，两组之间的组间差异性确切（χ2=9.017，P<0.05）。③实验组患者的并发症（3.33%）明显少于参照组（30.00%），差异无统计学意义（χ2=7.680，P<0.05）。④治疗前，实验组Frankel脊髓损伤级别为A、B、C、D、E分别有7例、7例、8例、5例、0例，对照组Frankel脊髓损伤级别为A、B、C、D、E分别有7例、6例、9例、8例、0例，两组患者治疗前Frankel脊髓损伤差异无统计学意义（P>0.05），治疗后，实验组Frankel脊髓损伤级别为A、B、C、D、E分别有0例、1例、2例、4例、23例，对照组Frankel脊髓损伤级别为A、B、C、D、E分别有0例、5例、5例、6例、14例，两组患者的Frankel脊髓损伤级别均有所改善，其中实验组的改善效果明显优于参照组，两组之间的组间差异有统计学意义（χ2=5.711，P<0.05）。⑤两组患者均没有明显的不良反应。⑥实验组患者治疗后的疼痛评分（1.68±0.66）分远低于参照组患者（3.22±0.58）分，两组之间的组间差异有统计学意义（t=15.4051，P<0.05）。 结论 老年性骨质疏松胸腰椎压缩性骨折患者实施补肾健骨汤联合西药治疗效果明显，一方面可以有效地促进患者的康复，另一方面可以有效的减少相关并发症的并发情况，且没有不良反应。
　　[关键词] 老年性骨质疏松胸腰椎压缩性骨折疾病;补肾健骨汤联合西药治疗;临床疗效;骨折
　　[中图分类号] R683          [文献标识码] A          [文章编号] 1674-0742（2020）03（a）-0169-05
　　Analysis of Clinical Efficacy of Combined Traditional Chinese and Western Medicine in Treating Osteoporotic Thoracolumbar Compression Fracture
　　LIU Feng-qiao
　　Department of Rehabilitation and General Practice， People's Hospital of Xishuangbanna Dai Autonomous Prefecture， Jinghong， Yunnan Province， 666100 China
　　[Abstract] Objective To study and analyze the effect and clinical efficacy of Bushen Jiangu decoction combined with western medicine on patients with osteoporotic thoracolumbar vertebral compression fractures. Methods Sixty patients with osteoporotic thoracolumbar vertebral compression fractures treated in the hospital were convenient selected from October 2017 to October 2018 as the time range of this study. They were divided into experimental group and reference group， using random number table method， 30 cases each. The reference group： pure western medicine treatment， the experimental group： Bushen Jiangu Decoction combined with western medicine treatment， compared the clinical treatment effect of the two groups of patients and the changes in bone density before and after treatment， Frankel's spinal cord before and after treatment in the two groups of patients Injury classification and the occurrence of complications and adverse reactions of the two combinations. The pain sensation of the two groups of patients was compared. The pain sensation measurement method was the pain simulation visual score. Results 1.Before treatment， the bone density of the experimental group was（-3 310.48±102.11） mg/cm3， the bone density of the control group was （-3 311.38±100.01）mg/cm3， and the two groups of senile osteoporotic thoracolumbar compression fractures bone mineral density of the patients was consistent（t=0.0344， P>0.05）. After treatment， the bone density of the experimental group was （-1 000.48±100.02）mg/cm3， and the bone density of the control group was （-1 408.48±103.21） mg/cm3. The bone mineral density of the two groups of patients was improved， and there was a significant difference compared with that before treatment （t=15.549， P<0.05）. The bone mineral density of patients in the experimental group was significantly better than that in the reference group， and there were significant differences between the two groups （P<0.05）. 2.The effective rate of clinical treatment for patients with thoracolumbar vertebral compression fractures of senile osteoporosis in the experimental group （96.66%） was higher than that in the reference group （66.66%）. The difference between the two groups is exact（χ2=9.017， P<0.05）. 3.The complications in the experimental group （3.33%） were significantly less than those in the reference group （30.00%）， and there were differences between the groups（χ2=7.680， P<0.05）. 4.Before treatment， Frankel's spinal cord injury levels in the experimental group were A， B， C， D， and E： 7， 7， 8， 5， and 0， respectively. In the control group， Frankel's spinal cord injury levels were A， B， and C. C， D， and E were 7， 6， 9， 9， and 0 respectively. There was no significant difference between Frankel's spinal cord injuries before treatment in the two groups. After treatment， Frankel's spinal cord injury levels in the experimental group were A， B， C， and D， E were 0， 1， 2， 4， 4 and 23 respectively. The control group Frankel's spinal cord injury levels were A， B， C， D， and E were 0， 5， 5， 6， and 14 cases， Frankel's spinal cord injury levels were improved in both groups. The improvement in the experimental group was significantly better than that in the reference group. The difference between the two groups was significant（χ2=5.711， P<0.05）. 5.There were no obvious adverse reactions in both groups. 6.The pain score after treatment in the experimental group （1.68±0.66） was much lower than that in the reference group （3.22±0.58）points， and the difference between the two groups was statistically significant（t=15.405， P<0.05）. Conclusion The effect of Bushen Jiangu Decoction combined with western medicine on elderly patients with osteoporotic thoracolumbar vertebral compression fractures is obvious. On the one hand， it can effectively promote the rehabilitation of patients， on the other hand， it can effectively reduce the complications of related complications， without side effects， which are worth further promotion and application.
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